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rosetteseptm human nk cell enrichment cocktail  (STEMCELL Technologies Inc)

 
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    STEMCELL Technologies Inc rosetteseptm human nk cell enrichment cocktail
    Rosetteseptm Human Nk Cell Enrichment Cocktail, supplied by STEMCELL Technologies Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/rosetteseptm human nk cell enrichment cocktail/product/STEMCELL Technologies Inc
    Average 90 stars, based on 1 article reviews
    rosetteseptm human nk cell enrichment cocktail - by Bioz Stars, 2026-03
    90/100 stars

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    Epitope binning analysis informs on mAb combinations that optimally avoid the induction of viral antibody escape variants. a) Pairwise competition measurement using SPR. b) Epitope binning from pairwise competition measurement. Blue colour symbolises the ability of a mAb pair to bind the antigen simultaneously, red colour indicates competition of a mAb pair for their epitope on the antigen. c) Virus escape assay using VSV∗ΔG-S in presence of the mAb cocktail MB021_C09K and MB025_A09L. d) Dose-dependent measurement of Fc-mediated effector functions (Antibody-dependent complement deposition [ADCD], cellular phagocytosis [ADCP], neutrophil phagocytosis [ADNP], and <t>NK</t> <t>cell</t> activation [ADNKA]) for the six mAbs in the epitope binning analysis. e) Effect of cocktail formulation on the Fc-mediated effector functions.
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    rosetteseptm human nk cell enrichment cocktail #15025  (STEMCELL Technologies Inc)
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    Epitope binning analysis informs on mAb combinations that optimally avoid the induction of viral antibody escape variants. a) Pairwise competition measurement using SPR. b) Epitope binning from pairwise competition measurement. Blue colour symbolises the ability of a mAb pair to bind the antigen simultaneously, red colour indicates competition of a mAb pair for their epitope on the antigen. c) Virus escape assay using VSV∗ΔG-S in presence of the mAb cocktail MB021_C09K and MB025_A09L. d) Dose-dependent measurement of Fc-mediated effector functions (Antibody-dependent complement deposition [ADCD], cellular phagocytosis [ADCP], neutrophil phagocytosis [ADNP], and <t>NK</t> <t>cell</t> activation [ADNKA]) for the six mAbs in the epitope binning analysis. e) Effect of cocktail formulation on the Fc-mediated effector functions.
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    Epitope binning analysis informs on mAb combinations that optimally avoid the induction of viral antibody escape variants. a) Pairwise competition measurement using SPR. b) Epitope binning from pairwise competition measurement. Blue colour symbolises the ability of a mAb pair to bind the antigen simultaneously, red colour indicates competition of a mAb pair for their epitope on the antigen. c) Virus escape assay using VSV∗ΔG-S in presence of the mAb cocktail MB021_C09K and MB025_A09L. d) Dose-dependent measurement of Fc-mediated effector functions (Antibody-dependent complement deposition [ADCD], cellular phagocytosis [ADCP], neutrophil phagocytosis [ADNP], and NK cell activation [ADNKA]) for the six mAbs in the epitope binning analysis. e) Effect of cocktail formulation on the Fc-mediated effector functions.

    Journal: eBioMedicine

    Article Title: Somatic hypermutation shapes the viral escape profile of SARS-CoV-2 neutralising antibodies

    doi: 10.1016/j.ebiom.2025.105770

    Figure Lengend Snippet: Epitope binning analysis informs on mAb combinations that optimally avoid the induction of viral antibody escape variants. a) Pairwise competition measurement using SPR. b) Epitope binning from pairwise competition measurement. Blue colour symbolises the ability of a mAb pair to bind the antigen simultaneously, red colour indicates competition of a mAb pair for their epitope on the antigen. c) Virus escape assay using VSV∗ΔG-S in presence of the mAb cocktail MB021_C09K and MB025_A09L. d) Dose-dependent measurement of Fc-mediated effector functions (Antibody-dependent complement deposition [ADCD], cellular phagocytosis [ADCP], neutrophil phagocytosis [ADNP], and NK cell activation [ADNKA]) for the six mAbs in the epitope binning analysis. e) Effect of cocktail formulation on the Fc-mediated effector functions.

    Article Snippet: NK cells were isolated from leucocyte reduction cones of aphaeresis donations from healthy donors using the RosetteSep NK cell enrichment Cocktail (STEMCELL Technologies, MA, USA) according to the manufacturer's instruction.

    Techniques: Virus, Activation Assay, Formulation